T cell receptor structural repertoire database

Welcome to the T cell receptor (TCR) structural repertoire database. Here we provide an easy-to-use interface to view all experimentally determined T cell receptor structures and their complexes. This includes complementarity determining region loops and analysis of interfaces with antigenic peptide and MHC.

We have also assembled a set of known TCR sequences from recent studies including TCR repertoire sequencing efforts.

The major goal of this site is to enable insights into the basis of TCR structure and recognition, to assist efforts in predictive modeling of this key component of the adaptive immune response, and to facilitate rational engineering of improved and novel immunotherapeutics.