Histogram of the binding affinities of TCR-pMHC complexes obtained from ATLAS database.
Buried surface area of all TCR interfaces that are in complex with different classes of MHC. Buried surface areas were calculated using the NACCESS program.
Shape complementarities of all TCR-peptide-MHC interfaces, for the same set of structures as above. Shape complementarity ranges from 0 (no complemenarity) to 1 (perfect complementarity), and values were calculated using the Sc algorithm in the CCP4 suite.